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Pure Transplant Solutions
High Resolution HLA Typing
Pure Transplant Solutions offers economical Sequence Based Typing (SBT) from our state-of-the-art, CLIA/ASHI certified laboratory. Our SBT service is built on the technology of Dr. William Hildebrand, an early pioneer in HLA sequencing who holds foundational intellectual property in the field. We have used a gold standard capillary electrophoresis method to type over 35,000 tissues to date, and we have data for virtually every HLA genotype and allele frequency for distinct populations, including Class I (HLA-A; HLA-B; HLA-C) and Class II (HLA-DRB1; HLA-DRB3,4,5; HLA-DQB1; HLA-DQA1).
Our Sequence Based Typing is an effective solution for:
- Vaccine Research
- Transplantation Diagnostics
- AutoImmune Disease Research
- HIV Research
Applications and Publications related to Sequence Based Typing
- Autoimmune Disease (Diabetes, Lupus, Spondylitis B27 ...)
- Virus Studies (HIV, Influenza...)
- Cutting Edge: Class I Presentation of Host Peptides Following HIV Infection
- Pure Protein L.L.C. Launches Hepatitis C Vaccine Discovery Project
- HLA Ligand Database and Peptide Predictions
- T-Cell Mediated Vaccine Studies
- Real-time measurement of in vitro peptide binding to soluble HLA-A*0201 by fluorescence polarization.
- CD8 T-Cell Recognition of Multiple Epitopes
- HLA Ligand (Peptide Predictions, Motifs ...)
- SBT Leaders
- CONTROL OF HIV-1 IS ASSOCIATED WITH HLA-B*13 AND TARGETING OF MULTIPLE GAG-SPECIFIC CD8+ T CELL EPITOPES
- Rhesus Macaque MHC Class I Molecules Present HLA-B-Like Peptides
- A high degree of HLA disparity arises from limited allelic diversity: analysis of 1775 unrelated bone marrow transplant donor-recipient pairs.
- Development and implementation of a direct detection, quantitation and validation system for class I MHC self-peptide epitopes.
- Levels of specific peptide-HLA class I complex predicts tumor cell susceptibility to CTL killing
- Development and Validation of a Fluorescence Polarization-Based Competitive Peptide Binding Assay – A New High-Throughput Screening Tool for Epitope Discovery (page 19)
- HLA-B15 Peptide Ligands Are Preferentially Anchored at Their C Termini
- Anti-Human Immunodeficiency Virus Type 1 (HIV-1) CD8+ T-Lymphocyte Reactivity during Combination Antiretroviral Therapy in HIV-1-Infected Patients with Advanced Immunodeficiency
- Cutting Edge: Class I Presentation of Host Peptides Following HIV Infection
©2007 - Pure Protein, L.L.C.